ProductHighlights:
TheTruSightMyeloidSequencingPanelusesexpert-definedcontentandprovennext-generationsequencing(NGS)technologytoidentifysomaticvariantsinmyeloidmalignancies.
Thepanelcontentwasdesignedbyaconsortiumofrecognizedexpertsinbloodcancerdisordersandtargetsgenesfrequentlymutatedin:
- Acutemyeloidleukemia(AML)
- Myelodysplasticsyndrome(MDS)
- Myeloproliferativeneoplasms(MPN)
- Chronicmyelogenousleukemia(CML)
- Chronicmyelomonocyticleukemia(CMML)
- Juvenilemyelomonocyticleukemia(JMML)
TheTruSightMyeloidSequencingPanelcovers15fullgenes(exonsonly)and39additionalgeneswhereoncogenichotspotsarecovered,providingacomprehensiveassessmentofthekeygenesknowntobeinvolvedinmyeloidmalignanciesinasingletest.Theresultisanaccurate,cost-effectivesolutionthatenablesresearcherstoprofileliquidtumors.
Viewthegenelist
TruSightMyeloidlibrariesareideallysuitedtorunonadesktopsequencerandperformalignmentandvariantcallingwiththeMiSeqReporterorLocalRunManagerAmpliconworkflowwithSomaticVariantCaller.FilteringandannotationcanthenbeperformedusingthefollowingIlluminaannotationandfilteringtools:BaseSpaceVariantInterpreterorVariantStudio.
Specifications:
| AssayTime | 8hours |
| Hands-OnTime | 3hours |
| InputQuantity | 50ng |
| SystemCompatibility | MiSeq,MiSeqDxinResearchMode,MiniSeq,NextSeq500 |
| Technology | Sequencing |
| VariantClass | SomaticVariants,Insertions-Deletions(indels) |
| SpeciesCategory | Human |
| CancerType | Hematological |
| Method | AmpliconSequencing,TargetedDNASequencing |
