ProductHighlights:
Targetinggenespreviouslylinkedtoapredispositiontowardscancer.
- DevelopedincollaborationwithProfessorNazneenRahmanandteamattheInstituteofCancerResearch(ICR),London
- Targets94genesand284SNPsassociatedwithapredispositiontowardscancer
TruSightCancerincludesgenesassociatedwithbothcommon(e.g.,breast,colorectal)andrarecancers.Inaddition,thesetincludes284SNPsfoundtocorrelatewithcancerthroughgenome-wideassociationstudies(GWAS).Contentselectionwasbasedonexpertcurationofthescientificliteratureandotherhigh-qualityresources.
TheTruSightCancersequencingpanelprovidescustomoligostargetingidentifiedregionsofinterest.Sufficientproductissuppliedforfourenrichmentreactions.TruSightCanceriscompatIBLewithTruSightRapidCapture.
TruSightCancerSampleDatasets
6humanreferencesampleswerepreparedusingtheTruSightCancersequencingpanel.TheselibrariesweresequencedontheMiniSeqSystemusingahighoutputkitata2x100bpreadlengthconfigurationwithdualindexing.Thetotalyieldwas5.2Gbwith95.8%ofbasesatoraboveQ30.
BrowsethedatainBaseSpaceSequenceHub:
- ViewRun
- ViewProject
*NotethataccesstothisdatarequiresaBaseSpaceSequenceHublogin.
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Specifications:
| AssayTime | 1.5days |
| InputQuantity | 50ng |
| SystemCompatibility | MiSeq,NextSeq550,MiSeqDxinResearchMode,MiniSeq,NextSeq500 |
| SpecializedSampleTypes | LowInput |
| Technology | Sequencing |
| SpeciesCategory | Human |
| VariantClass | GermlineVariants |
| CancerType | Pan-Cancer |
| Method | TargetedDNASequencing |
