ProductHighlights:
Targetinggenespreviouslylinkedtoapredispositiontowardscancer.
- DevelopedincollaborationwithProfessorNazneenRahmanandteamattheInstituteofCancerResearch(ICR),London
- Targets94genesand284SNPsassociatedwithapredispositiontowardscancer
TruSightCancerincludesgenesassociatedwithbothcommon(e.g.,breast,colorectal)andrarecancers.Inaddition,thesetincludes284SNPsfoundtocorrelatewithcancerthroughgenome-wideassociationstudies(GWAS).Contentselectionwasbasedonexpertcurationofthescientificliteratureandotherhigh-qualityresources.
TheTruSightCancersequencingpanelprovidescustomoligostargetingidentifiedregionsofinterest.Sufficientproductissuppliedforfourenrichmentreactions.TruSightCanceriscompatIBLewithTruSightRapidCapture.
TruSightCancerSampleDatasets
6humanreferencesampleswerepreparedusingtheTruSightCancersequencingpanel.TheselibrariesweresequencedontheMiniSeqSystemusingahighoutputkitata2x100bpreadlengthconfigurationwithdualindexing.Thetotalyieldwas5.2Gbwith95.8%ofbasesatoraboveQ30.
BrowsethedatainBaseSpaceSequenceHub:
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*NotethataccesstothisdatarequiresaBaseSpaceSequenceHublogin.
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Specifications:
AssayTime | 1.5days |
InputQuantity | 50ng |
SystemCompatibility | MiSeq,NextSeq550,MiSeqDxinResearchMode,MiniSeq,NextSeq500 |
SpecializedSampleTypes | LowInput |
Technology | Sequencing |
SpeciesCategory | Human |
VariantClass | GermlineVariants |
CancerType | Pan-Cancer |
Method | TargetedDNASequencing |